Profenofos 400 g/L + Cypermethrin 40 g/L EC: A Broad-Spectrum Insecticide for Modern Crop Protection
September 22, 2026
Learn about Profenofos 400 g/L + Cypermethrin 40 g/L EC, a broad-spectrum insecticide formulation combining two active ingredients for effective management of various agricultural insect pests.
Introduction
As agricultural production continues to face pressure from insect pests, growers and crop protection professionals are increasingly looking for insecticide formulations that provide reliable pest management while fitting into practical crop protection programs.
Profenofos 400 g/L + Cypermethrin 40 g/L EC is a combination insecticide formulated as an emulsifiable concentrate (EC). It combines the organophosphate insecticide profenofos with the pyrethroid insecticide cypermethrin, providing two different insecticidal modes of action within one formulation.
This combination is designed for broad-spectrum insect pest management and can be incorporated into integrated crop protection programs where the product is registered and recommended for the target crop and pest.
What Is Profenofos 400 g/L + Cypermethrin 40 g/L EC?
Profenofos 400 g/L + Cypermethrin 40 g/L EC contains:
- Profenofos: 400 g/L
- Cypermethrin: 40 g/L
- Formulation: Emulsifiable Concentrate (EC)
Profenofos belongs to the organophosphate group of insecticides, while cypermethrin belongs to the pyrethroid group.
The combination brings together active ingredients with different biochemical target sites. According to the IRAC classification, profenofos is classified as Group 1B, an acetylcholinesterase inhibitor, while cypermethrin belongs to Group 3A, the sodium channel modulator group.
The different mode-of-action groups make this formulation relevant to resistance-management strategies when used appropriately as part of a broader insecticide rotation program.
How Does the Combination Work?
Profenofos
Profenofos is an organophosphate insecticide that inhibits acetylcholinesterase (AChE). This interferes with normal nerve signal transmission in susceptible insects, ultimately resulting in loss of normal movement and insect death.
It has activity against several economically important insect pests and can provide contact and stomach insecticidal activity.
Cypermethrin
Cypermethrin is a synthetic pyrethroid that acts on voltage-gated sodium channels in the nervous system of susceptible insects.
By disrupting normal nerve transmission, cypermethrin can cause rapid excitation, paralysis and mortality in susceptible insect pests.
Complementary Insecticidal Activity
The combination of profenofos and cypermethrin provides two distinct insecticidal mechanisms:
Profenofos → IRAC Group 1B → Acetylcholinesterase inhibitor
Cypermethrin → IRAC Group 3A → Sodium channel modulator
This combination can provide broad-spectrum insect control while offering a formulation option for crop protection programs that require activity from different insecticide groups.
Target Insect Pests
Depending on local registration, crop, application rate and pest susceptibility, formulations containing profenofos and cypermethrin may be used for the management of different agricultural insect pests.
Potential target pest groups can include:
- Caterpillars and other lepidopteran larvae
- Thrips
- Aphids
- Plant bugs
- Certain beetles
- Other chewing and sucking insect pests
Important: The actual registered crops, target pests, application rates, pre-harvest intervals and permitted uses vary by country. Users should always follow the approved local product label and relevant agricultural regulations.
Potential Crop Applications
Profenofos + cypermethrin formulations may be considered for insect pest management in crops where the combination is locally registered.
Potential agricultural applications may include:
- Cotton
- Vegetables
- Fruit crops
- Field crops
- Other commercial crops
The appropriate crop and pest spectrum should always be determined according to the registration status and approved label in the target market.
Why Use a Combination Insecticide?
Modern crop protection increasingly emphasizes integrated pest management (IPM) rather than relying continuously on a single insecticide or mode of action.
A combination product can offer several practical advantages:
1. Broad-Spectrum Pest Management
The formulation combines two insecticidal active ingredients with activity against different insect pest groups, potentially making it suitable for situations involving mixed pest populations.
2. Different Modes of Action
Profenofos and cypermethrin belong to different IRAC mode-of-action groups. This is particularly relevant when designing insecticide rotation programs intended to reduce selection pressure associated with repeated use of the same mode of action.
3. Convenient Formulation
The EC formulation provides a concentrated liquid product that can be diluted with water according to the approved application instructions.
4. Flexible Crop Protection Programs
Where locally registered, the formulation can be incorporated into pest management programs alongside cultural, biological and other chemical control methods.
Resistance Management Considerations
Insecticide resistance is an important challenge for modern agriculture. Repeated exposure to insecticides with the same mode of action can increase selection pressure and contribute to the development of resistant pest populations.
For this reason, growers and agricultural professionals should consider:
- Rotating insecticides with different IRAC mode-of-action groups
- Avoiding unnecessary repeated applications
- Following recommended application rates
- Monitoring pest populations and treatment effectiveness
- Integrating biological and cultural control methods where appropriate
- Following local resistance-management recommendations
Although Profenofos 400 g/L + Cypermethrin 40 g/L EC combines two different insecticide groups, the combination should not be treated as a substitute for a comprehensive resistance-management program.
Profenofos + Cypermethrin EC for Professional Crop Protection
For pesticide distributors, agricultural companies and crop protection professionals, a combination formulation can provide an additional option for developing product portfolios targeting multiple insect pest categories.
The 400 g/L profenofos + 40 g/L cypermethrin EC formulation is particularly suitable for markets where customers require a concentrated broad-spectrum insecticide formulation and where the product has obtained the necessary local registration.
For international agricultural markets, factors such as formulation stability, packaging, labeling, registration requirements, application recommendations and local pest conditions should be considered before commercialization.
Customized Pesticide Manufacturing and Private Label Service
Averstar Industrial Co., Ltd. focuses on the manufacturing and export of agricultural pesticide products, including herbicides, insecticides and fungicides.
For international customers, we can provide customized solutions covering:
- Active ingredient and formulation selection
- EC, SC, SL, WP, WDG and other formulation types
- Private label and OEM service
- Customized packaging
- Different bottle and container sizes
- Customized labels and product designs
- Technical documentation such as COA and MSDS
- Registration support
- Product development according to local market requirements
We work with agricultural companies, pesticide distributors and other professional partners in international markets to develop crop protection products according to their specific market requirements.
Frequently Asked Questions
What is Profenofos 400 g/L + Cypermethrin 40 g/L EC?
It is a combination insecticide containing 400 g/L profenofos and 40 g/L cypermethrin in an emulsifiable concentrate formulation.
What type of insecticide is Profenofos?
Profenofos is an organophosphate insecticide classified by IRAC as Group 1B, an acetylcholinesterase inhibitor.
What type of insecticide is Cypermethrin?
Cypermethrin is a synthetic pyrethroid insecticide classified by IRAC as Group 3A, a sodium channel modulator.
What insects can Profenofos + Cypermethrin control?
Depending on the registered use, crop and local pest spectrum, the combination may be used against various chewing and sucking insect pests, including certain caterpillars, thrips, aphids, plant bugs and beetles.
Can this insecticide be used on all crops?
No. Crop uses, target pests, application rates and pre-harvest intervals depend on local registration and the approved product label. Always follow the regulations of the target country.
Can Averstar provide private label Profenofos + Cypermethrin EC?
Yes. Averstar can provide OEM/private label pesticide manufacturing, including customized packaging, labels, formulation specifications and other product requirements subject to technical feasibility and local regulatory requirements.
Conclusion
Profenofos 400 g/L + Cypermethrin 40 g/L EC combines two insecticidal active ingredients from different IRAC mode-of-action groups in one emulsifiable concentrate formulation.
With profenofos providing acetylcholinesterase-inhibiting activity and cypermethrin acting on sodium channels, the combination offers a broad-spectrum insecticide option for professional crop protection programs.
For agricultural companies and distributors seeking OEM insecticide manufacturing, customized pesticide formulations or private label crop protection products, Averstar can provide formulation and packaging solutions designed around the requirements of different international markets.
For product specifications, packaging options, registration support or customized Profenofos 400 g/L + Cypermethrin 40 g/L EC solutions, please contact Averstar Industrial Co., Ltd.
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